The short answer is yes.
However, you can increase the odds in your favour by cold calling intelligently. For example, speaking to the right person in the organisation will increase the likelihood of him or her being interested in learning more about what you do.
Calling at the right time in the day will also increase your odds of finding that person at his or her desk. Knowing his or her hot buttons will increase the prospect’s chances of asking for more information or being open to a meeting.